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A Novel Fluorogenic Assay for the Detection of Nephrotoxin-Induced Oxidative Stress in Live Cells and Renal Tissue

[Image: see text] Drug-induced kidney injury frequently leads to aborted clinical trials and drug withdrawals. Sufficiently sensitive sensors capable of detecting mild signs of chemical insult in cell-based screening assays are critical to identifying and eliminating potential toxins in the preclini...

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Detalles Bibliográficos
Autores principales: Mukherjee, Kamalika, Chio, Tak Ian, Gu, Han, Sackett, Dan L., Bane, Susan L., Sever, Sanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314269/
https://www.ncbi.nlm.nih.gov/pubmed/34214393
http://dx.doi.org/10.1021/acssensors.1c00422