Haemoglobin switching modulator SNPs rs5006884 is associated with increased HbA(2) in β-thalassaemia carriers

INTRODUCTION: Haemoglobin A(2) (HbA(2)), the tetramer of α- and δ-globin chains, is used as a diagnostic biomarker for β-thalassaemia carriers. The HbA(2) levels are regulated by the presence of HPFH, δ-thalassaemia, HbA(1/2) gene triplication, and variants of KLF1, β-globin gene, and HbF regulating...

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Detalles Bibliográficos
Autores principales: Cyrus, Cyril, Vatte, Chittibabu, Chathoth, Shahanas, Sayed, Abdul Azeez, Borgio, J. Francis, Alrubaish, Mohammed Abdullah, Alfalah, Rawan, Alsaikhan, Jana, Al Ali, Amein K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2019
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314410/
https://www.ncbi.nlm.nih.gov/pubmed/34336034
http://dx.doi.org/10.5114/aoms.2019.86705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314410/
https://www.ncbi.nlm.nih.gov/pubmed/34336034
http://dx.doi.org/10.5114/aoms.2019.86705

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