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Pharmacokinetics and safety of liposomal bupivacaine after local infiltration in healthy Chinese adults: a phase 1 study

BACKGROUND: Liposomal bupivacaine (LB) is a long-acting formulation of bupivacaine. The safety and efficacy of LB has been demonstrated across surgical procedures. However, pharmacokinetic (PK) parameters and safety of LB in the Chinese population have not been assessed. METHODS: In this single-arm,...

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Detalles Bibliográficos
Autores principales: Cheung, Bernard MY, Ng, Pauline Yeung, Liu, Ying, Zhou, Manman, Yu, Vincent, Yang, Julia, Wang, Natalie Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314475/
https://www.ncbi.nlm.nih.gov/pubmed/34315419
http://dx.doi.org/10.1186/s12871-021-01407-5