TLR2 deficiency promotes IgE and inhibits IgG1 class-switching following ovalbumin sensitization

BACKGROUND: To explore the roles of Toll-like receptor (TLR)2 in Th2 cytokine production and immunoglobulin (Ig) class switching following ovalbumin (OVA) sensitization. METHODS: TLR2(−/−) and wild-type C57BL/6 mice were sensitized by intraperitoneal injection with OVA. Lung pathology was assessed b...

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Detalles Bibliográficos
Autores principales: Li, Yuqin, Chen, Qiu, Ji, Wei, Fan, Yujie, Huang, Li, Chu, Chu, Zhou, Weifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314519/
https://www.ncbi.nlm.nih.gov/pubmed/34315511
http://dx.doi.org/10.1186/s13052-021-01088-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314519/
https://www.ncbi.nlm.nih.gov/pubmed/34315511
http://dx.doi.org/10.1186/s13052-021-01088-3

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