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TLR2 deficiency promotes IgE and inhibits IgG1 class-switching following ovalbumin sensitization
BACKGROUND: To explore the roles of Toll-like receptor (TLR)2 in Th2 cytokine production and immunoglobulin (Ig) class switching following ovalbumin (OVA) sensitization. METHODS: TLR2(−/−) and wild-type C57BL/6 mice were sensitized by intraperitoneal injection with OVA. Lung pathology was assessed b...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314519/ https://www.ncbi.nlm.nih.gov/pubmed/34315511 http://dx.doi.org/10.1186/s13052-021-01088-3 |