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SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation
BACKGROUND: Linear ubiquitination is a novel type of ubiquitination that plays important physiological roles in signalling pathways such as tumour necrosis factor (TNF) signalling. However, little is known about the regulatory mechanisms of linear ubiquitination, except the well-described enzymatic...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314547/ https://www.ncbi.nlm.nih.gov/pubmed/34315543 http://dx.doi.org/10.1186/s13578-021-00659-5 |