SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation

BACKGROUND: Linear ubiquitination is a novel type of ubiquitination that plays important physiological roles in signalling pathways such as tumour necrosis factor (TNF) signalling. However, little is known about the regulatory mechanisms of linear ubiquitination, except the well-described enzymatic...

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Detalles Bibliográficos
Autores principales: Shi, Ruona, Shi, Xue, Qin, Dajiang, Tang, Shibing, Vermeulen, Michiel, Zhang, Xiaofei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314547/
https://www.ncbi.nlm.nih.gov/pubmed/34315543
http://dx.doi.org/10.1186/s13578-021-00659-5

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