High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory disease

BACKGROUND: Differentiating infiltrating myeloid cells from resident microglia in neuroinflammatory disease is challenging, because bone marrow-derived inflammatory monocytes infiltrating the inflamed brain adopt a ‘microglia-like’ phenotype. This precludes the accurate identification of either cell...

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Detalles Bibliográficos
Autores principales: Spiteri, Alanna G., Terry, Rachel L., Wishart, Claire L., Ashhurst, Thomas M., Campbell, Iain L., Hofer, Markus J., King, Nicholas J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314570/
https://www.ncbi.nlm.nih.gov/pubmed/34311763
http://dx.doi.org/10.1186/s12974-021-02214-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314570/
https://www.ncbi.nlm.nih.gov/pubmed/34311763
http://dx.doi.org/10.1186/s12974-021-02214-y

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