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Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo

BACKGROUND: Osteoporosis is a major public health concern for the elderly population and is characterized by fatigue load resulting in bone microdamage. The ability of bone mesenchymal stem cells (BMSCs) to repair bone microdamage diminishes with age, and the accumulation of bone microdamage increas...

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Detalles Bibliográficos
Autores principales: Xun, Jingqiong, Li, Chan, Liu, Meilu, Mei, Yueming, Zhou, Qiongfei, Wu, Bo, Xie, Fen, Liu, Yuling, Dai, Ruchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314589/
https://www.ncbi.nlm.nih.gov/pubmed/34315544
http://dx.doi.org/10.1186/s13287-021-02449-9