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Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo
BACKGROUND: Osteoporosis is a major public health concern for the elderly population and is characterized by fatigue load resulting in bone microdamage. The ability of bone mesenchymal stem cells (BMSCs) to repair bone microdamage diminishes with age, and the accumulation of bone microdamage increas...
Autores principales: | Xun, Jingqiong, Li, Chan, Liu, Meilu, Mei, Yueming, Zhou, Qiongfei, Wu, Bo, Xie, Fen, Liu, Yuling, Dai, Ruchun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314589/ https://www.ncbi.nlm.nih.gov/pubmed/34315544 http://dx.doi.org/10.1186/s13287-021-02449-9 |
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