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Hyaluronic Acid Coated Liposomes Co-Delivery of Natural Cyclic Peptide RA-XII and Mitochondrial Targeted Photosensitizer for Highly Selective Precise Combined Treatment of Colon Cancer

BACKGROUND: Natural cyclopeptide RA-XII, isolated from Rubia yunnanensis, is a promising chemotherapeutic agent for colon cancer. The photosensitizer protoporphyrin-IX attached with triphenylphosphonium (TPP) could possess mitochondria targeting capacity and exert photodynamic therapy (PDT) by induc...

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Detalles Bibliográficos
Autores principales: Xu, Yanqing, Yao, Yongrong, Wang, Linxiao, Chen, Huachao, Tan, Ninghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314934/
https://www.ncbi.nlm.nih.gov/pubmed/34326635
http://dx.doi.org/10.2147/IJN.S311577