Cargando…

Cx43 deficiency confers EMT-mediated tamoxifen resistance to breast cancer via c-Src/PI3K/Akt pathway

Tamoxifen (TAM) resistance has indicated a significant challenge during endocrine therapy for hormone-sensitive breast cancer. Thus, it is significant to elucidate the molecular events endowing TAM resistance to endocrine therapy. In this study, we found that epithelial-mesenchymal transition (EMT)...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Deng-Pan, Zhou, Yan, Hou, Li-Xiang, Zhu, Xiao-Xiao, Yi, Wen, Yang, Si-Man, Lin, Tian-Yu, Huang, Jin-Lan, Zhang, Bei, Yin, Xiao-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315014/
https://www.ncbi.nlm.nih.gov/pubmed/34326682
http://dx.doi.org/10.7150/ijbs.55453