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Cisplatin Induces Pyroptosis via Activation of MEG3/NLRP3/caspase-1/GSDMD Pathway in Triple-Negative Breast Cancer

Cisplatin (DDP) was reported to improve pathological complete response (pCR) rates in triple-negative breast cancer (TNBC) patients, however, the molecular mechanism still remains largely unknown. Emerging evidence suggested that some chemotherapeutic drugs played anti-tumor effects by inducing cell...

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Detalles Bibliográficos
Autores principales: Yan, Honglin, Luo, Bin, Wu, Xiaoyan, Guan, Feng, Yu, Xinxin, Zhao, Lina, Ke, Xiaokang, Wu, Juan, Yuan, Jingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315016/
https://www.ncbi.nlm.nih.gov/pubmed/34326697
http://dx.doi.org/10.7150/ijbs.60292