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Aberrant FGFR4 signaling worsens nonalcoholic steatohepatitis in FGF21KO mice

Background: Nonalcoholic steatohepatitis (NASH) is the most severe form of non-alcoholic fatty liver disease (NAFLD) and a potential precursor of hepatocellular carcinoma (HCC). In our previous studies, we found that endocrine fibroblast growth factor 21 (FGF21) played a key role in preventing the d...

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Detalles Bibliográficos
Autores principales: Yu, Youxi, Shi, Xiaoju, Zheng, Qianqian, Wang, Xingtong, Liu, Xingkai, Tan, Min, Lv, Guoyue, Zhang, Ping, Martin, Robert C., Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315028/
https://www.ncbi.nlm.nih.gov/pubmed/34326695
http://dx.doi.org/10.7150/ijbs.58776