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MicroRNA-185-5p inhibits hepatic gluconeogenesis and reduces fasting blood glucose levels by suppressing G6Pase

Aims/hypothesis: MicroRNAs (miRNAs) are known to contribute to many metabolic diseases, including type 2 diabetes. This study aimed to investigate the roles and molecular mechanisms of miR-185-5p in the regulation of hepatic gluconeogenesis. Methods: MicroRNA high-throughput sequencing was performed...

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Detalles Bibliográficos
Autores principales: Zheng, Hui, Wan, Jian, Shan, Yi, Song, Xi, Jin, Jie, Su, Qing, Chen, Song, Lu, Xinyuan, Yang, Jialin, Li, Quanmin, Song, Yuping, Li, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315058/
https://www.ncbi.nlm.nih.gov/pubmed/34335967
http://dx.doi.org/10.7150/thno.46882