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Endothelial cell infection and dysfunction, immune activation in severe COVID-19

Rationale: Pulmonary vascular endotheliitis, perivascular inflammation, and immune activation are observed in COVID-19 patients. While the initial SARS-CoV-2 infection mainly infects lung epithelial cells, whether it also infects endothelial cells (ECs) and to what extent SARS-CoV-2-mediated pulmona...

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Detalles Bibliográficos
Autores principales: Qin, Zhongnan, Liu, Fengming, Blair, Robert, Wang, Chenxiao, Yang, Haoran, Mudd, Joseph, Currey, Joshua M, Iwanaga, Naoki, He, Jibao, Mi, Ren, Han, Kun, Midkiff, Cecily C., Alam, Mohammad Afaque, Aktas, Bertal H, Heide, Richard S Vander, Veazey, Ronald, Piedimonte, Giovanni, Maness, Nicholas J, Ergün, Süleyman, Mauvais-Jarvis, Franck, Rappaport, Jay, Kolls, Jay K., Qin, Xuebin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315069/
https://www.ncbi.nlm.nih.gov/pubmed/34335981
http://dx.doi.org/10.7150/thno.61810