Orthogonal targeting of osteoclasts and myeloma cells for radionuclide stimulated dynamic therapy induces multidimensional cell death pathways

Rationale: Multiple myeloma (MM) is a multifocal malignancy of bone marrow plasma cells, characterized by vicious cycles of remission and relapse that eventually culminate in death. The disease remains mostly incurable largely due to the complex interactions between the bone microenvironment (BME) a...

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Detalles Bibliográficos
Autores principales: Zheleznyak, Alexander, Mixdorf, Matthew, Marsala, Lynne, Prior, Julie, Yang, Xiaoxia, Cui, Grace, Xu, Baogang, Fletcher, Steven, Fontana, Francesca, Lanza, Gregory, Achilefu, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315072/
https://www.ncbi.nlm.nih.gov/pubmed/34335961
http://dx.doi.org/10.7150/thno.60757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315072/
https://www.ncbi.nlm.nih.gov/pubmed/34335961
http://dx.doi.org/10.7150/thno.60757

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