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Orthogonal targeting of osteoclasts and myeloma cells for radionuclide stimulated dynamic therapy induces multidimensional cell death pathways
Rationale: Multiple myeloma (MM) is a multifocal malignancy of bone marrow plasma cells, characterized by vicious cycles of remission and relapse that eventually culminate in death. The disease remains mostly incurable largely due to the complex interactions between the bone microenvironment (BME) a...
Autores principales: | Zheleznyak, Alexander, Mixdorf, Matthew, Marsala, Lynne, Prior, Julie, Yang, Xiaoxia, Cui, Grace, Xu, Baogang, Fletcher, Steven, Fontana, Francesca, Lanza, Gregory, Achilefu, Samuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315072/ https://www.ncbi.nlm.nih.gov/pubmed/34335961 http://dx.doi.org/10.7150/thno.60757 |
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