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STK39 promotes breast cancer invasion and metastasis by increasing SNAI1 activity upon phosphorylation

SNAI1 is widely regarded as a master driver of epithelial-mesenchymal transition (EMT) and associated with breast cancer progression and metastasis. This pro-malignant role is strongly linked to posttranslational modification, especially phosphorylation, which controls its protein levels and subcell...

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Detalles Bibliográficos
Autores principales: Qiu, Zhaoping, Dong, Bo, Guo, Weijie, Piotr, Rychahou, Longmore, Greg, Yang, Xiuwei, Yu, Zhiyong, Deng, Jiong, Evers, B. Mark, Wu, Yadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315073/
https://www.ncbi.nlm.nih.gov/pubmed/34335956
http://dx.doi.org/10.7150/thno.62406