Impaired Priming of SARS-CoV-2-Specific Naive CD8(+) T Cells in Older Subjects

Advanced age is associated with severe symptoms and death upon SARS-CoV-2 infection. Virus-specific CD8(+) T-cell responses have shown to be protective toward critical COVID-19 manifestations, suggesting that suboptimal cellular immunity may contribute to the age-pattern of the disease. The inductio...

Descripción completa

Detalles Bibliográficos
Autores principales: Gallerani, Eleonora, Proietto, Davide, Dallan, Beatrice, Campagnaro, Marco, Pacifico, Salvatore, Albanese, Valentina, Marzola, Erika, Marconi, Peggy, Caputo, Antonella, Appay, Victor, Gavioli, Riccardo, Nicoli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315546/
https://www.ncbi.nlm.nih.gov/pubmed/34326844
http://dx.doi.org/10.3389/fimmu.2021.693054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315546/
https://www.ncbi.nlm.nih.gov/pubmed/34326844
http://dx.doi.org/10.3389/fimmu.2021.693054

Ejemplares similares