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Impaired Priming of SARS-CoV-2-Specific Naive CD8(+) T Cells in Older Subjects

Advanced age is associated with severe symptoms and death upon SARS-CoV-2 infection. Virus-specific CD8(+) T-cell responses have shown to be protective toward critical COVID-19 manifestations, suggesting that suboptimal cellular immunity may contribute to the age-pattern of the disease. The inductio...

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Detalles Bibliográficos
Autores principales:	Gallerani, Eleonora, Proietto, Davide, Dallan, Beatrice, Campagnaro, Marco, Pacifico, Salvatore, Albanese, Valentina, Marzola, Erika, Marconi, Peggy, Caputo, Antonella, Appay, Victor, Gavioli, Riccardo, Nicoli, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315546/ https://www.ncbi.nlm.nih.gov/pubmed/34326844 http://dx.doi.org/10.3389/fimmu.2021.693054

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