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High shear stress enhances endothelial permeability in the presence of the risk haplotype at 9p21.3

Single nucleotide polymorphisms (SNPs) are exceedingly common in non-coding loci, and while they are significantly associated with a myriad of diseases, their specific impact on cellular dysfunction remains unclear. Here, we show that when exposed to external stressors, the presence of risk SNPs in...

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Detalles Bibliográficos
Autores principales: Teng, Evan L., Masutani, Evan M., Yeoman, Benjamin, Fung, Jessica, Lian, Rachel, Ngo, Brenda, Kumar, Aditya, Placone, Jesse K., Lo Sardo, Valentina, Engler, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315817/
https://www.ncbi.nlm.nih.gov/pubmed/34327295
http://dx.doi.org/10.1063/5.0054639