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High shear stress enhances endothelial permeability in the presence of the risk haplotype at 9p21.3
Single nucleotide polymorphisms (SNPs) are exceedingly common in non-coding loci, and while they are significantly associated with a myriad of diseases, their specific impact on cellular dysfunction remains unclear. Here, we show that when exposed to external stressors, the presence of risk SNPs in...
Autores principales: | Teng, Evan L., Masutani, Evan M., Yeoman, Benjamin, Fung, Jessica, Lian, Rachel, Ngo, Brenda, Kumar, Aditya, Placone, Jesse K., Lo Sardo, Valentina, Engler, Adam J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AIP Publishing LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315817/ https://www.ncbi.nlm.nih.gov/pubmed/34327295 http://dx.doi.org/10.1063/5.0054639 |
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