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Coelacanth SERINC2 Inhibits HIV-1 Infectivity and Is Counteracted by Envelope Glycoprotein from Foamy Virus

SERINC5 restricts nef-defective HIV-1 by affecting early steps of the virus life cycle. Distantly related retroviruses with a wide host range encode virulent factors in response to challenge by SERINC5. However, the evolutionary origins of this antiretroviral activity, its prevalence among the paral...

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Detalles Bibliográficos
Autores principales: Ramdas, Pavitra, Bhardwaj, Vipin, Singh, Aman, Vijay, Nagarjun, Chande, Ajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316019/
https://www.ncbi.nlm.nih.gov/pubmed/33883219
http://dx.doi.org/10.1128/JVI.00229-21