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In Vivo Generation of BK and JC Polyomavirus Defective Viral Genomes in Human Urine Samples Associated with Higher Viral Loads

Defective viral genomes (DVGs) are parasitic viral sequences containing point mutations, deletions, or duplications that might interfere with replication. DVGs are often associated with viral passage at high multiplicities of infection in culture systems but have been increasingly reported in clinic...

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Detalles Bibliográficos
Autores principales: Addetia, Amin, Phung, Quynh, Bradley, Benjamin T., Lin, Michelle J., Zhu, Haiying, Xie, Hong, Huang, Meei-Li, Greninger, Alexander L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316075/
https://www.ncbi.nlm.nih.gov/pubmed/33827948
http://dx.doi.org/10.1128/JVI.00250-21