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A Bioinformatics Whole-Genome Sequencing Workflow for Clinical Mycobacterium tuberculosis Complex Isolate Analysis, Validated Using a Reference Collection Extensively Characterized with Conventional Methods and In Silico Approaches

The use of whole-genome sequencing (WGS) for routine typing of bacterial isolates has increased substantially in recent years. For Mycobacterium tuberculosis (MTB), in particular, WGS has the benefit of drastically reducing the time required to generate results compared to most conventional phenotyp...

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Detalles Bibliográficos
Autores principales: Bogaerts, Bert, Delcourt, Thomas, Soetaert, Karine, Boarbi, Samira, Ceyssens, Pieter-Jan, Winand, Raf, Van Braekel, Julien, De Keersmaecker, Sigrid C. J., Roosens, Nancy H. C., Marchal, Kathleen, Mathys, Vanessa, Vanneste, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316078/
https://www.ncbi.nlm.nih.gov/pubmed/33789960
http://dx.doi.org/10.1128/JCM.00202-21