Cargando…

Efficacy and Associated Drug Exposures of Isavuconazole and Fluconazole in an Experimental Model of Coccidioidomycosis

Coccidioides spp. are important pathogens in regions where they are endemic, and new treatment options are needed. Here, isavuconazonium sulfate (ISAVUSULF) and fluconazole (FLU) were evaluated in experimental disseminated coccidioidomycosis to characterize drug exposures associated with efficacy. B...

Descripción completa

Detalles Bibliográficos
Autores principales: Kovanda, Laura L., Sass, Gabriele, Martinez, Marife, Clemons, Karl V., Nazik, Hasan, Kitt, Therese M., Wiederhold, Nathan, Hope, William W., Stevens, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316117/
https://www.ncbi.nlm.nih.gov/pubmed/33782009
http://dx.doi.org/10.1128/AAC.02344-20