The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology

Relapsing fever (RF), caused by spirochetes of the genus Borrelia, is a globally distributed, vector-borne disease with high prevalence in developing countries. To date, signaling pathways required for infection and virulence of RF Borrelia spirochetes are unknown. Cyclic di-AMP (c-di-AMP), synthesi...

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Detalles Bibliográficos
Autores principales: Jackson-Litteken, Clay D., Ratliff, C. Tyler, Kneubehl, Alexander R., Siletti, Cheta, Pack, Lindsay, Lan, Renny, Huynh, TuAnh N., Lopez, Job E., Blevins, Jon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Molecular Pathogenesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316131/
https://www.ncbi.nlm.nih.gov/pubmed/33846120
http://dx.doi.org/10.1128/IAI.00787-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316131/
https://www.ncbi.nlm.nih.gov/pubmed/33846120
http://dx.doi.org/10.1128/IAI.00787-20

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