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The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
Relapsing fever (RF), caused by spirochetes of the genus Borrelia, is a globally distributed, vector-borne disease with high prevalence in developing countries. To date, signaling pathways required for infection and virulence of RF Borrelia spirochetes are unknown. Cyclic di-AMP (c-di-AMP), synthesi...
Autores principales: | Jackson-Litteken, Clay D., Ratliff, C. Tyler, Kneubehl, Alexander R., Siletti, Cheta, Pack, Lindsay, Lan, Renny, Huynh, TuAnh N., Lopez, Job E., Blevins, Jon S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316131/ https://www.ncbi.nlm.nih.gov/pubmed/33846120 http://dx.doi.org/10.1128/IAI.00787-20 |
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