Cargando…

Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2

Astrocytes are a viable source for generating new neurons via direct conversion. However, little is known about the neurogenic cascades triggered in astrocytes from different regions of the CNS. Here, we examine the transcriptome induced by the proneural factors Ascl1 and Neurog2 in spinal cord-deri...

Descripción completa

Detalles Bibliográficos
Autores principales: Kempf, J., Knelles, K., Hersbach, B.A., Petrik, D., Riedemann, T., Bednarova, V., Janjic, A., Simon-Ebert, T., Enard, W., Smialowski, P., Götz, M., Masserdotti, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316252/
https://www.ncbi.nlm.nih.gov/pubmed/34289357
http://dx.doi.org/10.1016/j.celrep.2021.109409