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Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2
Astrocytes are a viable source for generating new neurons via direct conversion. However, little is known about the neurogenic cascades triggered in astrocytes from different regions of the CNS. Here, we examine the transcriptome induced by the proneural factors Ascl1 and Neurog2 in spinal cord-deri...
Autores principales: | Kempf, J., Knelles, K., Hersbach, B.A., Petrik, D., Riedemann, T., Bednarova, V., Janjic, A., Simon-Ebert, T., Enard, W., Smialowski, P., Götz, M., Masserdotti, G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316252/ https://www.ncbi.nlm.nih.gov/pubmed/34289357 http://dx.doi.org/10.1016/j.celrep.2021.109409 |
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