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Inter-eye genomic heterogeneity in bilateral retinoblastoma via aqueous humor liquid biopsy

Germline alterations in the RB1 tumor suppressor gene predispose patients to develop retinoblastoma (RB) in both eyes. While similar treatment is given for each eye, there is often a variable therapeutic response between the eyes. Herein, we use the aqueous humor (AH) liquid biopsy to evaluate the c...

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Detalles Bibliográficos
Autores principales: Wong, Elyssa Y., Xu, Liya, Shen, Lishuang, Kim, Mary E., Polski, Ashley, Prabakar, Rishvanth K., Shah, Rachana, Jubran, Rima, Kim, Jonathan W., Biegel, Jaclyn A., Gai, Xiaowu, Kuhn, Peter, Hicks, James, Berry, Jesse L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316348/
https://www.ncbi.nlm.nih.gov/pubmed/34316014
http://dx.doi.org/10.1038/s41698-021-00212-0