STING suppresses bone cancer pain via immune and neuronal modulation

Patients with advanced stage cancers frequently suffer from severe pain as a result of bone metastasis and bone destruction, for which there is no efficacious treatment. Here, using multiple mouse models of bone cancer, we report that agonists of the immune regulator STING (stimulator of interferon...

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Detalles Bibliográficos
Autores principales: Wang, Kaiyuan, Donnelly, Christopher R., Jiang, Changyu, Liao, Yihan, Luo, Xin, Tao, Xueshu, Bang, Sangsu, McGinnis, Aidan, Lee, Michael, Hilton, Matthew J., Ji, Ru-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316360/
https://www.ncbi.nlm.nih.gov/pubmed/34315904
http://dx.doi.org/10.1038/s41467-021-24867-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316360/
https://www.ncbi.nlm.nih.gov/pubmed/34315904
http://dx.doi.org/10.1038/s41467-021-24867-2

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