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Elemental mapping of labelled biological specimens at intermediate energy loss in an energy‐filtered TEM acquired using a direct detection device

The technique of colour EM that was recently developed enabled localisation of specific macromolecules/proteins of interest by the targeted deposition of diaminobenzidine (DAB) conjugated to lanthanide chelates. By acquiring lanthanide elemental maps by energy‐filtered transmission electron microsco...

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Detalles Bibliográficos
Autores principales: Ramachandra, Ranjan, Mackey, Mason R., Hu, Junru, Peltier, Steven T., Xuong, Nguyen‐Huu, Ellisman, Mark H., Adams, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316382/
https://www.ncbi.nlm.nih.gov/pubmed/33844293
http://dx.doi.org/10.1111/jmi.13014