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Shotgun lipidomics of liver and brain tissue of Alzheimer’s disease model mice treated with acitretin

Alzheimer’s disease (AD) is a very frequent neurodegenerative disorder characterized by an accumulation of amyloid-β (Aβ). Acitretin, a retinoid-derivative and approved treatment for Psoriasis vulgaris, increases non-amyloidogenic Amyloid-Precursor-Protein-(APP)-processing, prevents Aβ-production an...

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Detalles Bibliográficos
Autores principales: Lauer, Anna A., Janitschke, Daniel, dos Santos Guilherme, Malena, Nguyen, Vu Thu Thuy, Bachmann, Cornel M., Qiao, Sen, Schrul, Bianca, Boehm, Ulrich, Grimm, Heike S., Hartmann, Tobias, Endres, Kristina, Grimm, Marcus O. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316403/
https://www.ncbi.nlm.nih.gov/pubmed/34315969
http://dx.doi.org/10.1038/s41598-021-94706-3