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Shotgun lipidomics of liver and brain tissue of Alzheimer’s disease model mice treated with acitretin
Alzheimer’s disease (AD) is a very frequent neurodegenerative disorder characterized by an accumulation of amyloid-β (Aβ). Acitretin, a retinoid-derivative and approved treatment for Psoriasis vulgaris, increases non-amyloidogenic Amyloid-Precursor-Protein-(APP)-processing, prevents Aβ-production an...
Autores principales: | Lauer, Anna A., Janitschke, Daniel, dos Santos Guilherme, Malena, Nguyen, Vu Thu Thuy, Bachmann, Cornel M., Qiao, Sen, Schrul, Bianca, Boehm, Ulrich, Grimm, Heike S., Hartmann, Tobias, Endres, Kristina, Grimm, Marcus O. W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316403/ https://www.ncbi.nlm.nih.gov/pubmed/34315969 http://dx.doi.org/10.1038/s41598-021-94706-3 |
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