Dynamic BH3 profiling identifies active BH3 mimetic combinations in non-small cell lung cancer

Conventional chemotherapy is still of great utility in oncology and rationally constructing combinations with it remains a top priority. Drug-induced mitochondrial apoptotic priming, measured by dynamic BH3 profiling (DBP), has been shown in multiple cancers to identify drugs that promote apoptosis...

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Detalles Bibliográficos
Autores principales: Potter, Danielle S., Du, Ruochen, Bhola, Patrick, Bueno, Raphael, Letai, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316436/
https://www.ncbi.nlm.nih.gov/pubmed/34315868
http://dx.doi.org/10.1038/s41419-021-04029-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316436/
https://www.ncbi.nlm.nih.gov/pubmed/34315868
http://dx.doi.org/10.1038/s41419-021-04029-4

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