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Dynamic BH3 profiling identifies active BH3 mimetic combinations in non-small cell lung cancer
Conventional chemotherapy is still of great utility in oncology and rationally constructing combinations with it remains a top priority. Drug-induced mitochondrial apoptotic priming, measured by dynamic BH3 profiling (DBP), has been shown in multiple cancers to identify drugs that promote apoptosis...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316436/ https://www.ncbi.nlm.nih.gov/pubmed/34315868 http://dx.doi.org/10.1038/s41419-021-04029-4 |