The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging

Multifunctional N6-methyladenosine (m6A) has been revealed to be an important epigenetic component in various physiological and pathological processes, but its role in female ovarian aging remains unclear. Thus, we demonstrated m6A demethylase FTO downregulation and the ensuing increased m6A in gran...

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Detalles Bibliográficos
Autores principales: Jiang, Zhong-xin, Wang, Yi-ning, Li, Zi-yuan, Dai, Zhi-hui, He, Yi, Chu, Kun, Gu, Jia-yi, Ji, Yi-Xuan, Sun, Ning-xia, Yang, Fu, Li, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316443/
https://www.ncbi.nlm.nih.gov/pubmed/34315853
http://dx.doi.org/10.1038/s41419-021-04016-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316443/
https://www.ncbi.nlm.nih.gov/pubmed/34315853
http://dx.doi.org/10.1038/s41419-021-04016-9

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