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The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging
Multifunctional N6-methyladenosine (m6A) has been revealed to be an important epigenetic component in various physiological and pathological processes, but its role in female ovarian aging remains unclear. Thus, we demonstrated m6A demethylase FTO downregulation and the ensuing increased m6A in gran...
Autores principales: | Jiang, Zhong-xin, Wang, Yi-ning, Li, Zi-yuan, Dai, Zhi-hui, He, Yi, Chu, Kun, Gu, Jia-yi, Ji, Yi-Xuan, Sun, Ning-xia, Yang, Fu, Li, Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316443/ https://www.ncbi.nlm.nih.gov/pubmed/34315853 http://dx.doi.org/10.1038/s41419-021-04016-9 |
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