Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis

The NLRP3 inflammasome mediates the production of proinflammatory cytokines and initiates inflammatory cell death. Although NLRP3 is essential for innate immunity, aberrant NLRP3 inflammasome activation contributes to a wide variety of inflammatory diseases. Understanding the pathways that control N...

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Detalles Bibliográficos
Autores principales: Mayes-Hopfinger, Lindsey, Enache, Aura, Xie, Jian, Huang, Chou-Long, Köchl, Robert, Tybulewicz, Victor L. J., Fernandes-Alnemri, Teresa, Alnemri, Emad S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316491/
https://www.ncbi.nlm.nih.gov/pubmed/34315884
http://dx.doi.org/10.1038/s41467-021-24784-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316491/
https://www.ncbi.nlm.nih.gov/pubmed/34315884
http://dx.doi.org/10.1038/s41467-021-24784-4

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