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Structural basis for genome packaging, retention, and ejection in human cytomegalovirus

How the human cytomegalovirus (HCMV) genome—the largest among human herpesviruses—is packaged, retained, and ejected remains unclear. We present the in situ structures of the symmetry-mismatched portal and the capsid vertex-specific components (CVSCs) of HCMV. The 5-fold symmetric 10-helix anchor—un...

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Detalles Bibliográficos
Autores principales: Li, Zhihai, Pang, Jingjing, Dong, Lili, Yu, Xuekui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316551/
https://www.ncbi.nlm.nih.gov/pubmed/34315863
http://dx.doi.org/10.1038/s41467-021-24820-3