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Super-resolution microscopy reveals that Na(+)/K(+)-ATPase signaling protects against glucose-induced apoptosis by deactivating Bad

Activation of the apoptotic pathway is a major cause of progressive loss of function in chronic diseases such as neurodegenerative and diabetic kidney diseases. There is an unmet need for an anti-apoptotic drug that acts in the early stage of the apoptotic process. The multifunctional protein Na(+),...

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Detalles Bibliográficos
Autores principales: Bernhem, Kristoffer, Fontana, Jacopo M., Svensson, Daniel, Zhang, Liang, Nilsson, Linnéa M., Scott, Lena, Blom, Hans, Brismar, Hjalmar, Aperia, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316575/
https://www.ncbi.nlm.nih.gov/pubmed/34315852
http://dx.doi.org/10.1038/s41419-021-04025-8