Nox1/4 inhibition exacerbates age dependent perivascular inflammation and fibrosis in a model of spontaneous hypertension

Hypertension is associated with oxidative stress and perivascular inflammation, critical contributors to perivascular fibrosis and accelerated vascular ageing. Oxidative stress can promote vascular inflammation, creating options for potential use of NADPH oxidase inhibitors in pharmacological target...

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Detalles Bibliográficos
Autores principales: Nosalski, R., Mikolajczyk, T., Siedlinski, M., Saju, B., Koziol, J., Maffia, P., Guzik, T.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316606/
https://www.ncbi.nlm.nih.gov/pubmed/33131726
http://dx.doi.org/10.1016/j.phrs.2020.105235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316606/
https://www.ncbi.nlm.nih.gov/pubmed/33131726
http://dx.doi.org/10.1016/j.phrs.2020.105235

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