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Tanshinol Alleviates Microcirculation Disturbance and Impaired Bone Formation by Attenuating TXNIP Signaling in GIO Rats

Impaired bone formation is the main characteristics of glucocorticoid (GC)-induced osteoporosis (GIO), which can be ameliorated by tanshinol, an aqueous polyphenol isolated from Salvia miltiorrhiza Bunge. However, the underlying mechanism is still not entirely clear. In the present study, we determi...

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Detalles Bibliográficos
Autores principales: Lai, Wenxiu, Mo, Yulin, Wang, Dongtao, Zhong, Ying, Lu, Lujiao, Wang, Jiajia, Cui, Liao, Liu, Yanzhi, Yang, Yajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316650/
https://www.ncbi.nlm.nih.gov/pubmed/34335280
http://dx.doi.org/10.3389/fphar.2021.722175