Local Cisplatin Delivery in Mouse Reliably Models Sensorineural Ototoxicity Without Systemic Adverse Effects

Cisplatin is a lifesaving chemotherapeutic drug with marked ototoxic adverse effects. Cisplatin-induced hearing loss affects a significant part of cancer-surviving patients and is an unmet clinical need with important socioeconomic consequences. Unfortunately, in current preclinical animal models of...

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Detalles Bibliográficos
Autores principales: Nacher-Soler, German, Lenglet, Sébastien, Coelho, Marta, Thomas, Aurélien, Voruz, François, Krause, Karl-Heinz, Senn, Pascal, Rousset, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316727/
https://www.ncbi.nlm.nih.gov/pubmed/34335192
http://dx.doi.org/10.3389/fncel.2021.701783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316727/
https://www.ncbi.nlm.nih.gov/pubmed/34335192
http://dx.doi.org/10.3389/fncel.2021.701783

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