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Local Cisplatin Delivery in Mouse Reliably Models Sensorineural Ototoxicity Without Systemic Adverse Effects
Cisplatin is a lifesaving chemotherapeutic drug with marked ototoxic adverse effects. Cisplatin-induced hearing loss affects a significant part of cancer-surviving patients and is an unmet clinical need with important socioeconomic consequences. Unfortunately, in current preclinical animal models of...
Autores principales: | Nacher-Soler, German, Lenglet, Sébastien, Coelho, Marta, Thomas, Aurélien, Voruz, François, Krause, Karl-Heinz, Senn, Pascal, Rousset, Francis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316727/ https://www.ncbi.nlm.nih.gov/pubmed/34335192 http://dx.doi.org/10.3389/fncel.2021.701783 |
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