Pharmacological Modulation of Ion Channels for the Treatment of Cystic Fibrosis

Cystic fibrosis (CF) is a life-shortening monogenic disease caused by mutations in the gene encoding the CF transmembrane conductance regulator (CFTR) protein, an anion channel that transports chloride and bicarbonate across epithelia. Despite clinical progress in delaying disease progression with s...

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Detalles Bibliográficos
Autores principales: Pinto, Madalena C, Silva, Iris A L, Figueira, Miriam F, Amaral, Margarida D, Lopes-Pacheco, Miquéias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316759/
https://www.ncbi.nlm.nih.gov/pubmed/34326672
http://dx.doi.org/10.2147/JEP.S255377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316759/
https://www.ncbi.nlm.nih.gov/pubmed/34326672
http://dx.doi.org/10.2147/JEP.S255377

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