Allele-specific multi-sample copy number segmentation in ASCAT

MOTIVATION: Allele-specific copy number alterations are commonly used to trace the evolution of tumours. A key step of the analysis is to segment genomic data into regions of constant copy number. For precise phylogenetic inference, breakpoints shared between samples need to be aligned to each other...

Descripción completa

Detalles Bibliográficos
Autores principales: Ross, Edith M., Haase, Kerstin, Van Loo, Peter, Markowetz, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317109/
https://www.ncbi.nlm.nih.gov/pubmed/32449758
http://dx.doi.org/10.1093/bioinformatics/btaa538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317109/
https://www.ncbi.nlm.nih.gov/pubmed/32449758
http://dx.doi.org/10.1093/bioinformatics/btaa538

Ejemplares similares