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Allele-specific multi-sample copy number segmentation in ASCAT
MOTIVATION: Allele-specific copy number alterations are commonly used to trace the evolution of tumours. A key step of the analysis is to segment genomic data into regions of constant copy number. For precise phylogenetic inference, breakpoints shared between samples need to be aligned to each other...
Autores principales: | Ross, Edith M., Haase, Kerstin, Van Loo, Peter, Markowetz, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317109/ https://www.ncbi.nlm.nih.gov/pubmed/32449758 http://dx.doi.org/10.1093/bioinformatics/btaa538 |
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